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Symbol Name ID |
Pparg
peroxisome proliferator activated receptor gamma MGI:97747 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Loss of facial adipose tissue |
Reduced subcutaneous adipose tissue |
Loss of gluteal subcutaneous adipose tissue |
Loss of subcutaneous adipose tissue in limbs |
Lipodystrophy |
Lipoatrophy |
| Disease(s) Associated with PPARG | ||||||
| familial partial lipodystrophy type 3 |
| Mouse Phenotypes | adipose tissue phenotype |
decreased brown adipose tissue amount |
absent subcutaneous adipose tissue |
decreased subcutaneous adipose tissue amount |
abnormal white adipose tissue amount |
decreased white adipose tissue amount |
decreased total body fat amount |
increased total body fat amount |
abnormal adipose tissue distribution |
decreased body fat mass |
abnormal brown adipose tissue morphology |
decreased brown adipose tissue mass |
abnormal brown fat cell morphology |
decreased brown fat cell lipid droplet size |
increased brown fat cell lipid droplet size |
decreased brown fat cell number |
abnormal brown fat cell size |
increased brown fat cell size |
decreased brown fat lipid droplet number |
abnormal fat cell morphology |
abnormal fat cell differentiation |
abnormal white fat cell morphology |
decreased white fat cell number |
abnormal white fat cell size |
decreased white fat cell size |
increased white fat cell size |
decreased fat cell size |
increased fat cell size |
abnormal epididymal fat pad morphology |
decreased epididymal fat pad weight |
abnormal gonadal fat pad morphology |
decreased gonadal fat pad weight |
abnormal inguinal fat pad morphology |
decreased inguinal fat pad weight |
decreased retroperitoneal fat pad weight |
abnormal interscapular fat pad morphology |
decreased interscapular fat pad weight |
increased interscapular fat pad weight |
decreased total fat pad weight |
decreased percent body fat/body weight |
abnormal white adipose tissue morphology |
decreased white adipose tissue mass |
lipodystrophy |
abnormal adipose tissue physiology |
increased adipocyte glucose uptake |
abnormal white adipose tissue physiology |
|
| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||||||||||
| Ppargtm1.1Auw/Ppargtm1.1Auw | * | ||||||||||||||||||||||||||||||||||||||||||||||
| Ppargtm1Auw/Ppargtm1Auw | |||||||||||||||||||||||||||||||||||||||||||||||
| Ppargtm1Laz/Ppargtm1Laz | |||||||||||||||||||||||||||||||||||||||||||||||
| Ppargtm1Yec/Ppargtm1Yec | |||||||||||||||||||||||||||||||||||||||||||||||
| Ppargtm2Avp/Ppargtm2Avp | |||||||||||||||||||||||||||||||||||||||||||||||
| Ppargtm1Avp/Pparg+ | |||||||||||||||||||||||||||||||||||||||||||||||
| Ppargtm1b(KOMP)Wtsi/Pparg+ | |||||||||||||||||||||||||||||||||||||||||||||||
| Ppargtm1Lja/Pparg+ | |||||||||||||||||||||||||||||||||||||||||||||||
| Ppargtm1Mae/Pparg+ | |||||||||||||||||||||||||||||||||||||||||||||||
| Ppargtm1Tka/Pparg+ | |||||||||||||||||||||||||||||||||||||||||||||||
| Ppargtm1Uls/Pparg+ | |||||||||||||||||||||||||||||||||||||||||||||||
| Ppargtm2(tTA)Yba/Pparg+ | * | ||||||||||||||||||||||||||||||||||||||||||||||
| Ppargtm3(tTA)Yba/Pparg+ | |||||||||||||||||||||||||||||||||||||||||||||||
| Ppargtm1.2Mtz/Ppargtm1.2Mtz Tg(Fabp4-cre/ERT2)1Ipc/0 (conditional) |
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| Ppargtm2Rev/Ppargtm2Rev Tg(Fabp4-cre)1Rev/0 (conditional) |
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| Ppargtm2Rev/Ppargtm2Rev Tg(Ucp1-cre)1Evdr/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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